goals prioritization, mental health and irrational beliefs are concept much discussed nowadays. This study aims to compare the goals prioritization of the students and its relation to mental health and irrational beliefs. This study was designed and completed descriptively. The sample included 216 students of AllamehTabatabai University. Students completed the Goals and Aspirations, Mental Health and Irrational Beliefs questionnaires.Although there was no significant difference between the goals prioritization and total scale of mental health and irrational beliefs and just in the symptoms of depression and helplessness against the change subscales differences were significant and the number of people who had given priority to the physical goals, were significantly more than other people. According to the mean of data in terms of mental health and the irrational beliefs, people who had given priority to the self superiority goals, are better than those of their priorities is related to physical goals.