The present study aimed to examine the mediating roles of self-coherence and cognitive flexibility in the relationship between marital dissatisfaction and attitudes toward divorce among women seeking divorce. The study employed a descriptive correlational design. The statistical population consisted of all women seeking divorce who referred to counseling clinics in Sabzevar during the winter of 2024, from whom 205 women were selected as the study sample using convenience sampling. The variables were assessed using the Divorce Attitude Scale (DAS), Cognitive Flexibility Inventory (CFI), Sense of Coherence Questionnaire (SOC), and Marital Burnout Questionnaire (MBQ). Descriptive and correlational analyses were conducted using SPSS version 22, and structural equation modeling was performed using AMOS version 22. The results of the correlation analysis indicated that marital dissatisfaction was positively and significantly associated with attitudes toward divorce among women seeking divorce (p<.05). The results of the structural equation modeling showed that marital dissatisfaction had a significant indirect effect on attitudes toward divorce through self-coherence (p<.05); however, its indirect effect on attitudes toward divorce through cognitive flexibility was not significant (p>.05). Overall, the model, including marital dissatisfaction, self-coherence, and cognitive flexibility, explained 68% of the variance in attitudes toward divorce. Based on these findings, self-coherence plays a mediating role in the relationship between marital dissatisfaction and attitudes toward divorce, whereas no evidence was found for a mediating role of cognitive flexibility in this relationship.